Mitotic Inhibitor

Paclitaxel Albumin Encapsulated – Available as Lyophilized powder/100mg vials & Nano Particles (Patent Non infringing)

Paclitaxel Nano-Pellets for Injection. Paclitaxel is a mitotic inhibitor drip used in the treatment of cancer.

• MKPPL is the only the sixth company in India to have developed successfully nab-paclitaxel, the other companies being Cipla, Sun Pharma, Cadila-Zydus, Intas and Natco.
• The particle size and the encapsulation efficiency have matched the innovator’s specifications.
• In vitro cell line studies have shown that the activity is comparable to the innovator.
• Offer complete technical package for registrations in all regulated/semi regulated markets.

Paclitaxel (protein-bound particles) for Injectable Suspension

• Nab Paclitaxel is a ground-breaking chemotherapy medication.
• It is uniquely formulated as an albumin-bound nanoparticle, which enhances both its efficacy and safety.
• Nab Paclitaxel is utilized in the treatment of breast cancer, pancreatic cancer, and non-small cell lung cancer.
• Administration is typically via intravenous infusion.

Revolutionizing Cancer Care with Nab Paclitaxel Treatment

Advantages of Nab Paclitaxel:

• Enhanced Solubility: The nanoparticle form of Nab Paclitaxel improves its solubility in water, facilitating easier administration.
• Targeted Delivery: Nano-sized particles exhibit a preference for accumulating at tumor sites, boosting the drug’s effectiveness.
• Reduced Side Effects: Nab Paclitaxel nanoparticles evade recognition by healthy tissues, thereby minimizing adverse
  effects.
• Higher Dosing: This enables the use of higher maximum tolerated doses (MTD).
• Improved Pharmacokinetics: Longer half-life and superior tumor accumulation.

The Significance of Encapsulation:

• Encapsulation of paclitaxel is crucial for precise targeting while minimizing side effects.
• Conventional systemic administration affects healthy cells throughout the body.
• Encapsulation guarantees that the drug efficiently reaches the tumor site.