Products

Aprepitant Pellets 40.0% – Ready to Fill Into Capsules (Dose: 40 mg, 80 mg, or 125 mg)

• Matches with the innovator product in terms of the dissolution profile
• Conducted and cleared multimedia dissolution studies against the innovator product
• Offers a non-infringing product
• Do offer development services in case of a requirement for different formulation/dosage/strength
• Offer complete technical package for registrations in all regulated/semi regulated markets

Azithromycin Pellets/Powder 7.5%, 20%, 40% – Suitable for Capsules, Tablets, Suspension

• The objective of developing Azithromycin taste masked micro pellets (Multiple unit particulate system i.e. MUPS) by aqueous technology is to fill the micro pellets in to capsule, are compressed into tablet and also are constituted to make the oral suspension. MUPS has distinct advantages over single unit system such as multiple unit particles get distributed throughout the Gl tract thereby avoiding localized accumulation. Micro pellets developed by aqueous technology have also advantage of avoiding the use of organic solvents.
• We do offer development services in case of a requirement for different formulation/dosage/strength
• Offer complete technical package for registrations in all regulated/semi regulated markets
• Products protected by ongoing Patents are not offered by MKPPL.

Brinzolamide Opthalmic Nano Suspension 1% W/V – Suitable for Suspension (Dose: 10 mg/ml)

• MKPPL developed a Nano particle based matrix which can deliver hydrophilic as well as hydrophobic drugs using a combination of hydrophilic and hydrophobic excipients as a clear solution. This cogent use of excipients ensures that the drug is absorbed optimally and the Nano particles ensure that the drug penetrates not only through the hydrophobic and hydrophilic channels but also through the OraSerrata which protects the eye from any foreign body entering the optical cavity.
• The formulation is in form of a clear solution and is available in the same concentration as the innovator i.e. 10 mg/ml.  The product can be offered as a solution that can be sterile filtered and filled.
• We do offer development services in case of a requirement for different formulation/dosage/strength
• Offer complete technical package for registrations in all regulated/semi regulated markets
• Products protected by ongoing Patents are not offered by MKPPL.

Brinzolamide Eye Drop – (Nano suspension 1% w/v)

The Nano emulsion developed by Murli Krishna Pharma ensures the following:

• Nano particle based matrix, which can deliver hydrophilic as well as hydrophobic drugs using a combination of hydrophilic and hydrophobic excipients as a clear solution. This cogent use of excipients ensures that the drug is absorbed optimally and the Nano particles ensure that the drug penetrates not only through the hydrophobic and hydrophilic channels but also through the OraSerrata, which protects the eye from any foreign body entering the optical cavity.
• The protein binding is minimized due to encapsulation.
• The particle size is to the tune of 100 nm which makes the product easily sterile filterable.
• The formulation is in form of a clear solution and is available in the same concentration as the innovator i.e. 10 mg/ml. The product can be offered as a solution that can be sterile filtered and filled.
• We offer development services in case of a requirement for different formulation/dosage/strength
• Offer complete technical package for registrations in all regulated/semi regulated markets
• Products protected by ongoing Patents are not offered by MKPPL.

Budesonide Pellets 0.8% -Available as Nano solution/Soft Mist & Ready to fill in Capsules.

• Release pattern compared with innovator
• MKPPL have entrapped 5 mg of drug in 1 ml of the nanoparticle formulation, whereas in the innovator formulation 0.25 mg is dispersed in 2 ml.
• MKPPL also standardized bud clear suspension (5mg/ml) which is 10 times the concentration of the innovator.
• Stability proves that the nanoparticles are stable and could be optimized.
• The release extends up to 24 hours to reach 100%.
• Offer complete technical package for registrations in all regulated/semi regulated markets.

Budesonide Soft Mist Inhaler, 100mg

Clarithromycin Taste Masked Granules 27.5%, 30%, 33%, 42%, 43.75% – Suitable for Capsules, Tablets, Suspensions (DOSE: 125 mg, 250 mg, 500 mg)

Clarithromycin is used to treat a wide variety of bacterial infections including the one’s caused by H. PYLORI. This medication can also be used in combination with anti-ulcer medications to treat certain types of stomach ulcers. It may also be used to prevent certain bacterial infections.

• Murli Krishna Pharma Pvt. Ltd. is a leading global PFI manufacturer and supplier for Clarithromycin PFI as granules.
• The process of Manufacturing Clarithromycin Taste Masked Pellets of MKPPL is completely aqueous based. No solvent has been used in any stage of manufacturing process. This process effectively masks the taste of the drug without compromising the dissolution rate.
• We offer development services if different formulation/dosage/strength are required.
• Complete technical package for registrations in all regulated/semi regulated markets are available
• Products protected by ongoing Patents are not offered by MKPPL.